Showing posts with label Brain. Show all posts
Showing posts with label Brain. Show all posts

Saturday, October 6, 2012

B12 Levels Predict a Healthier Brain

A study that analyzed the vitamin B121 levels in elderly individuals, age 61-87, found that higher B12 levels were associated with more normal brain size. On the other hand, those with the lowest levels of B12 had the most brain atrophy and were six times more likely to have a problem. 

The study does not talk about B12 deficiency from the point of view of government standards or daily values; people with the lowest B12 levels in this study were not actually deficient according to these standards. However, if one’s brain is shrinking due to a “low-normal” level of a vitamin, then most people would consider that a rather flagrant deficiency of a nutrient.

While supplements were not directly tested in this study to see whether or not they could prevent or reverse the problem, the data suggests that taking B12 is a really good idea for brain health. 

Vitamin B12 is vital to nerve function, as determined by hundreds of studies. Of course, I recommend supplementation with the co-enzyme forms of B12 such as methylcobalamin. Never use the cyanide-producing form known as cyanocobalamin, which is found in many dietary supplements.

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Supplements that contain coenzyme B12
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Saturday, September 15, 2012

Magnesium Boosts Brain Function

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Thursday, September 6, 2012

Study: Brain disease deaths high in NFL veterans

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Thursday, August 23, 2012

Watch: Brain Tumors That Glow

Plane Crash in Idaho Forest Caught on...More Popular VideoChris Christie to Deliver Keynote at GOP...Inside the Mormon ChurchFeds: Animals Abused at School Beef SupplierMissing Oregon Boy Kyron Horman's Stepmother...World's Oldest Man Turns 115In The NewsU.S.PoliticsEntertainmentWeird and WackyBrain Tumors That Glow Neurosurgeons at Indiana University Health are first in the nation to use a special visual-aid.08/23/2012Share:

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Thursday, August 2, 2012

Training the brain for a mind-blowing 100 final

Reuters – 2 hrs 49 mins ago LONDON (Reuters) - It is hard to believe a race that lasts barely 10 seconds can seriously mess up your mind but when it is the Olympic 100 meters final, there is little doubt it can.

Intrusive thoughts about failure and humiliation can plague sprinters for months before a race. The constant stress then starts to interfere with hormones in the brain, making sleep, concentration and training suffer.

As Jamaicans Asafa Powell and Usain Bolt know well, one false start can wreck hopes before a race has even begun and haunt the psyche for years.

While endless honing of fitness and form is crucial for the world's fastest human beings, it may be brain training that makes the difference between glory and defeat.

"By the time they reach this level, elite athletes are fit, they're fast, they've done their homework, they know who they're up against. So it's hardly ever a skills issue," said Pieter Kruger, a London-based sports psychologist who has worked with many elite athletes including the 2012 British Olympic team.

"At this point it becomes about the application of skills under pressure - that's where the psychology comes in."

On the face of it, the men most likely to be lining up for the 100 final on Sunday August 5 seem very different.

Sprint king Bolt, a laid back, light-hearted showman, is rarely lacking in confidence and appears far more relaxed than compatriot Powell - a known worrier who has struggled to get over pre-race nerves in the past.

America's fastest man Tyson Gay is softly spoken and humble, keen to avoid bold predictions and pre-race posturing.

He has found the psychological aspects of training, especially when coming back after an injury, particularly tough.

"When you're a little bit banged up it plays on you mentally a lot because you realize you only need to be 100 percent, feeling good, for one race - and that's the final," he said.

Powell knows he must ignore his rivals and focus on his own performance.

"I should just stay composed and run to the finish line," he told Reuters earlier this year. "You don't want any doubts in your head.

CONTROL THE CONTROLLABLES

Sports psychologists agree that is exactly the right approach but is far easier said than done.

"One of the worst things athletes have to deal with is something called anticipatory anxiety," explained Kruger.

"These are very intrusive thoughts. They start in the weeks leading up to a big race and they're often very much focused on outcome goals - in other words 'I need to win, I've spent four years training for this, I don't want to fail'."

If athletes cannot get a grip on these fears, they build to a point that produces a state of almost continual stress, triggering a constant secretion of the stress hormones cortisol and adrenaline in the body.

"That can really interfere with sleep patterns, recovery, training, rest - and when we're talking about milliseconds of difference between a first and a fifth place, all these things become incredibly important," said Kruger.

What team psychologists and coaches need to do is help athletes redirect those thoughts towards the process rather than the outcome, so their minds are focused on how to run their best race, not on obsessing about whether or not they can win.

"It's about controlling the controllables," said Kruger. "You can't control the outcome but you can control everything else in the process."

In a list of the top 10 questions an athlete must be able to answer correctly, American 400 meters great Michael Johnson said a crucial one is "What really matters right now?"

The answer? "The only thing that matters is the race you are about to run. The focus required to compete at this level and under this pressure requires an athlete to be totally in the moment".

Damon Burton and Thomas Raedeke, authors of "Sports Psychology for Coaches" suggest sprinters should have a clear race plan, possibly with cue words for each phase, and should mentally rehearse their race until it becomes second nature.

"Thinking too much is the worst possible thing they can do psychologically," said Burton, a professor of sport psychology at University of Idaho in the United States.

"You want sprinters in that situation to keep their minds clear, stick to a routine, react to the gun, and just do what they can do as best as they possibly can," he said in a telephone interview.

"The worst thing is if they start having nagging self doubts in the back of their minds."

So far at least, Bolt seems to have got that message.

"I have no worries," he told Reuters on Thursday. "It is not over-confidence. I know what I can do."

(Editing by Justin Palmer)



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Wednesday, July 25, 2012

Snacking and BMI linked to double effect of brain activity and self-control

ScienceDaily (July 23, 2012) — Snack consumption and BMI are linked to both brain activity and self-control, new research has found.

See Also:Health & MedicineDiet and Weight LossBrain TumorObesityMind & BrainDieting and Weight ControlIntelligencePsychologyLiving WellReferenceBody mass indexOverweightAppetiteLimbic system

The research, carried out by academics from the Universities of Exeter, Cardiff, Bristol, and Bangor, discovered that an individual's brain 'reward centre' response to pictures of food predicted how much they subsequently ate. This had a greater effect on the amount they ate than their conscious feelings of hunger or how much they wanted the food,

A strong brain response was also associated with increased weight (BMI), but only in individuals reporting low levels of self-control on a questionnaire. For those reporting high levels of self-control a stronger brain response to food was actually related to a lower BMI.

This study, which is now published in the journal NeuroImage, adds to mounting evidence that overeating and increased weight are linked, in part, to a region of the brain associated with motivation and reward, called the nucleus accumbens. Responses in this brain region have been shown to predict weight gain in healthy weight and obese individuals, but only now have academics discovered that this is independent of conscious feelings of hunger, and that self-control also plays a key role.

Following these results, academics at the University of Exeter and Cardiff have begun testing 'brain training' techniques designed to reduce the influence of food cues on individuals who report low levels of self-control. Similar tests are being used to assist those with gambling or alcohol addiction.

Dr Natalia Lawrence of Psychology at the University of Exeter, lead researcher in both the original research and the new studies, said: "Our research suggests why some individuals are more likely to overeat and put on weight than others when confronted with frequent images of snacks and treats. Food images, such as those used in advertising, cause direct increases in activity in brain 'reward areas' in some individuals but not in others. If those sensitive individuals also struggle with self-control, which may be partly innate, they are more likely to be overweight. We are now developing computer programs that we hope will counteract the effects of this high sensitivity to food cues by training the brain to respond less positively to these cues."

Twenty-five young, healthy females with BMIs ranging from 17-30 were involved in the study. Female participants were chosen because research shows females typically exhibit stronger responses to food-related cues. The hormonal changes during the menstrual cycle affect this reaction, so all participants were taking the monophasic combined oral contraceptive pill. Participants had not eaten for at least six hours to ensure they were hungry at the time of the scan and were given a bowl containing 150 g (four and a half packets) of potato chips to eat at the end of the study; they were informed that potato chip intake had been measured afterwards.

Researchers used MRI scanning to detect the participants' brain activity while they were shown images of household objects, and food that varied in desirability and calorific content. After scanning, participants rated the food images for desirability and rated their levels of hunger and food craving. Results showed that participants' brain responses to food (relative to objects) in the nucleus accumbens predicted how many potato chips they ate after the scan. However, participants' own ratings of hunger and how much they liked and wanted the foods, including potato chips, were unrelated to their potato chip intake.

This study was funded by the Wales Institute of Cognitive Neuroscience.

What this study shows:

Brain responses to food images vary considerably between individuals. Brain responses to food images but not conscious feelings of hunger or desire to eat predict subsequent potato chip consumption. Individuals' reported levels of self-control influence whether this brain response is associated with a higher or lower BMI.

What this study does NOT show:

Brain responses to food cues cause overeating. The associations reported here are true in everyone -- only healthy young women were included. Whether our brain response and levels of self-control are learned or innate.Share this story on Facebook, Twitter, and Google:

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Wednesday, July 18, 2012

Sodium Buildup in Brain Linked to Disability in MS Patients

HealthDay – 2 hrs 1 min ago TUESDAY, July 17 (HealthDay News) -- Sodium buildup in the brain seems to be linked to disability in people with multiple sclerosis, researchers have found.

This accumulation of sodium could be an indicator of the degeneration of nerve cells that results from the disease, according to a team of European researchers. Although multiple sclerosis, or MS, symptoms vary from patient to patient, the study authors suggested that their findings may help predict the severity of disease progression and disability.

"A major challenge with multiple sclerosis is providing patients with a prognosis of disease progression. It's very hard to predict the course of the disease," Patrick Cozzone, director emeritus of the Center for Magnetic Resonance in Biology and Medicine, a joint unit of National Center for Scientific Research and Aix-Marseille University in Marseille, France, said in a news release from the Radiological Society of North America.

In conducting the study, the researchers used a specific type of imaging technology that provides information on the sodium content of cells in the body, known as 3 Tesla sodium MRI. The test was performed on 26 patients with relapsing-remitting MS, the most common form of the disease, in which flare-ups of symptoms are followed by periods of recovery.

Of the study's participants, 14 had early stage relapsing-remitting MS and 12 had advanced forms of the disease. The researchers also examined 15 healthy participants without MS that they matched for the patients' ages and genders.

"We collaborated for two years with chemists and physicists to develop techniques to perform

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Thursday, July 12, 2012

Brain Scans Using New Dye May Predict Alzheimer's

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Friday, July 6, 2012

Photos: Pencil Removed from Tot's Brain

Flesh-Eating Bacteria Victim Aimee...More Health HeadlinesMom Awakens After Birth in Near-ComaIn The NewsArthritisAllergiesDr. Richard BesserCold & FluHome > HealthPencil Lodged in 2-Year-Old's BrainWren Bowell fell on the pencil, which pierced her eye socket. PHOTOS: Pencil Lodged in 2-Year-Old's Brain

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Monday, July 2, 2012

Study of Retired NFL Players Finds Evidence of Brain Damage

HealthDay – Fri, Jun 29, 2012 FRIDAY, June 29 (HealthDay News) -- Tests performed on a group of retired NFL players revealed that more than 40 percent suffered from problems such as depression and dementia, adding to a growing pile of evidence that repeated sports-related head traumas can lead to lasting neurological issues.

Analyzing 34 ex-professional football players (average age 62) on benchmarks such as memory, reasoning, problem-solving and behavior, researchers from the Center for Brain Health at the University of Texas at Dallas found that 20 tested normal while the rest suffered from depression, various deficits in memory/thinking or a combination of these issues. Twenty-six of the players also underwent MRI scans.

"We picked up that many guys were depressed but didn't know it," added study author Dr. John Hart, medical science director at the center. "The cognitive impairments . . . were more than what's expected for their ages. A lot had damage to their brain's white matter, so for us it's a real clue or marker to look for."

Hart is scheduled to present the findings Friday at the National Athletic Trainers' Association (NATA) annual meeting in St. Louis. Research presented at scientific meetings should be considered preliminary until it is published in a peer-reviewed medical journal.

An estimated 300,000 sports-related concussions occur in the United States each year, and mounting attention is being paid to the neurological toll of those injuries on former professional athletes. In June, a massive bundle of lawsuits representing more than 2,100 National Football League players was filed against the league, claiming that the NFL hid information linking football-related head injuries to permanent brain damage.

Hart's study involved ex-NFL athletes hailing from the North Texas region. For comparison purposes, the researchers also looked at the brains of 26 people with no signs of mental deficits, selected from the general population and matched for age, education and IQ.

Of the eight former players who were found to have depression -- the finding that most surprised Hart -- most didn't exhibit the mood issues such as sadness that are typically associated with the condition, he said.

Instead, "there was a lack of energy, initiative or sex drive and disrupted sleep, with weight gain or loss," Hart said. "They would ruminate or get anxious about stuff, but they weren't crying. They were shocked or surprised

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Monday, June 25, 2012

Tracking Love, Lust in the Brain

HealthDay – 1 hr 22 mins ago FRIDAY, June 22 (HealthDay News) -- Love and sexual desire activate different but related areas of the brain, according to a new study.

Researchers analyzed data from 20 studies that monitored brain activity in people while engaged in activities such as viewing erotic pictures or photographs of their romantic partners.

This meta-analysis led to a map of love and desire in the brain, which shows that two structures called the insula and the striatum are involved in the progression from sexual desire to love.

"No one has ever put these two together to see the patterns of activation," study co-author Jim Pfaus, professor of psychology at Concordia University in Montreal, said in a university news release. "We didn't know what to expect -- the two could have ended up being completely separate. It turns out that love and desire activate specific but related areas in the brain."

The researchers found that love and sexual desire activate different areas of the striatum. The area activated by sexual desire is the same one that is activated by pleasurable activities such as sex or food. The area activated by love is where things associated with reward or pleasure are given a value.

The area activated by love also is associated with drug addiction, the researchers said.

"Love is actually a habit that is formed from sexual desire as desire is rewarded," Pfaus explained. "It works the same way in the brain as when people become addicted to drugs."

He also noted that love activates pathways in the brain involved in monogamy and pair bonding, and added that some areas in the brain are less active when people feel love than when they feel desire.

"While sexual desire has a very specific goal, love is more abstract and complex," Pfaus said. "It's less dependent on the physical presence of someone else."

The study conclusions should be considered preliminary until published in a peer-reviewed medical journal.

More information

Your Amazing Brain has more about the science of love.



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Friday, June 15, 2012

Omega-3 Supplements May Not Aid Aging Brain

HealthDay – 4 mins 38 secs ago WEDNESDAY, June 13 (HealthDay News) -- Taking omega-3 fatty acid supplements, such as fish oil capsules, doesn't seem to help older people maintain their brain health, researchers report.

A number of studies have suggested that omega-3 fatty acids may help keep nerve cells in the brain healthy into old age, but there is limited evidence for the role of these fatty acids in preventing dementia or decreased mental abilities -- known as "cognitive decline."

To examine this issue more closely, Emma Sydenham and colleagues at the London School of Hygiene & Tropical Medicine in England reviewed evidence from three studies that compared the effects of omega-3 fatty acids taken in capsules or margarine to the effects of placebo capsules with sunflower oil or olive oil, or regular margarine (the "control" group).

The studies included a total of more than 3,500 people over the age of 60 and lasted between six and 40 months. None of the participants showed any signs of problems with their thinking skills or dementia at the start of the studies.

People who consumed omega-3 fatty acid-containing capsules or margarine did no better on standard tests of mental abilities or on tests of memory and verbal skills, according to the findings published in The Cochrane Library.

"From these studies, there doesn't appear to be any benefit for cognitive health for older people of taking omega-3 supplements," report co-author Alan Dangour, a nutritionist at the London School of Hygiene & Tropical Medicine, said in a Cochrane news release.

"However, these were relatively short-term studies, so we saw very little deterioration in cognitive function in either the intervention groups or the control groups. It may take much longer to see any effect of these supplements," he added.

The researchers said further studies are needed to assess the long-term effects of omega-3 fatty acids on mental decline, particularly in people with low dietary intake of omega-3 fatty acids.

Oily fish such as salmon and mackerel are a source of omega-3 fatty acids and other health benefits. "Fish is an important part of a healthy diet and we would still support the recommendation to eat two portions a week, including one portion of oily fish," said Dangour.

More information

The Society of Neuroscience has more about aging and the brain.



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Thursday, June 14, 2012

Freezer damages brain samples used to study autism

A freezer malfunctioned at a Harvard-affiliated hospital that oversees the world's largest collection of autistic brain samples, damaging a third of the scientifically precious specimens and casting doubt on whether they can be used in research.

The director of the Harvard Brain Tissue Resource Center said the loss was "devastating," particularly in light of the increasing demand for brain samples among scientists searching for the cause of autism and potential treatments.

"Over the last 10 years, the autism tissue program has been working very hard to get the autism community to understand the importance of brain donation," Dr. Francine Benes said. Now many of those samples have been compromised.

The freezer failed sometime late last month at the center, which is housed at McLean Hospital in the Boston suburb of Belmont. At least 54 samples earmarked for autism research were harmed. Many of them turned dark with decay.

However, an initial review indicates that the DNA in the samples is intact and can still be used for genetic research. It's unclear, however, whether the samples could be used for the full range of neuroscience needs.

Thirty-two of the brains had been cut in half, with one side placed in a formaldehyde solution and the other placed in the freezer. The samples in the solution remain available for all research projects, the hospital said.

The frozen tissue samples are normally maintained at about minus 80 degrees Celsius, but the temperature had reached about 7 degrees

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Sunday, June 10, 2012

Skin Cells Turned Into Brain Cells in Lab Study

HealthDay – 54 mins ago THURSDAY, June 7 (HealthDay News) -- Scientists who reprogrammed skin cells into brain cells say their research could lay the groundwork for new ways to treat Alzheimer's and other brain diseases.

The team at the Gladstone Institutes in San Francisco transferred a gene called Sox2 into both mouse and human skin cells. Within days, the skin cells transformed into early-stage brain stem cells called induced neural stem cells.

These cells began to self-renew and soon matured into neurons capable of transmitting electrical signals. Within a month, these new neurons had developed into neural networks, according to the research published online June 7 in the journal Cell Stem Cell.

These transformed cells could provide better models for testing new drugs to treat Alzheimer's and other brain diseases, the researchers said.

"Many drug candidates -- especially those developed for neurodegenerative diseases -- fail in clinical trials because current models don't accurately predict the drug's effects on the human brain," Gladstone investigator Dr. Yadong Huang, who is also an associate professor of neurology at the University of California, San Francisco, said in a Gladstone news release.

"Human neurons -- derived from reengineered skin cells -- could help assess the efficacy and safety of these drugs, thereby reducing risks and resources associated with human trials," Huang explained.

About 5.4 million people in the United States have Alzheimer's disease and that number is expected to triple by 2050., the release notes. Currently, there are no approved drug treatments to prevent or reverse the disease.

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.



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Friday, May 25, 2012

Brain Injuries: New Concerns for Young Football Players

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Sunday, May 20, 2012

'Bad' Fat May Hurt Brain Function Over Time

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Tuesday, May 8, 2012

Late NFL star Seau's family undecided on brain research

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Scientists "switch off" brain cell death in mice

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Friday, May 4, 2012

Blueberries and Strawberries Reduce the Rate of Brain Aging

Researchers followed the intake of berries in a group of women participating in the Nurses’ Health Study for more than 20 years.  They observed that women who had higher berry intake, especially blueberries but also strawberries, delayed cognitive aging by up to 2.5 years.

“As the U.S. population ages, understanding the health issues facing this group becomes increasingly important,” said Dr. Elizabeth Devore with Brigham and Women’s Hospital and Harvard Medical School in Boston, Mass. “Our study examined whether greater intake of berries could slow rates of cognitive decline.  We provide the first epidemiologic evidence that berries may slow progression of cognitive decline in elderly women.  Our findings have significant public health implications as increasing berry intake is a fairly simple dietary modification to test cognition protection in older adults.”

America is facing an aging population and an epidemic of cognitive decline related issues, including Alzheimer’s disease.  Increasing berry intake is relatively easy and should be done by everyone at any age.  Dietary supplements with concentrations of the active components of the berries are another effective and convenient way to boost intake.

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Clues to 'Slacker' Behavior Found in Brain, Study Says

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