Friday, June 15, 2012

Diabetes drug may help fight cancer, but no proof yet

Reuters – 1 hr 41 mins ago (Reuters) - A cheap and relatively safe diabetes drug, metformin, might have cancer-fighting properties, according to an international study - but findings fall short of proving it actually can stave off cancer.

Researchers, whose findings were published in the Journal of Clinical Oncology, found that women with diabetes who took the medication had a 25 percent lower risk of developing breast cancer over more than a decade of follow-up.

"Metformin use in postmenopausal women with diabetes was associated with lower incidence of invasive breast cancer," wrote lead researcher Rowan Chlebowski, at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center.

"These results can inform future studies evaluating metformin use in breast cancer management and prevention."

Metformin, also sold under the brand name Glucophage, has been on the market for many years and is generally considered safe, although five to 10 percent of patients experience side effects like nausea and bloating.

It is used by millions of type 2 diabetics every day to help control their blood sugar, and studies have shown it also shrinks lung and breast tumors in mice. Several reports show people taking it for diabetes appear to develop cancer less often.

The new study used data from about 68,000 postmenopausal women who took part in the U.S. government-funded Women's Health Initiative clinical trials.

Over nearly 12 years of observation, there were more than 3,200 new cases of breast cancer among the women.

Every year, 0.42 percent of women without diabetes developed breast cancer, compared to 0.40 percent of diabetics on metformin and 0.47 percent of diabetics taking other drugs.

After taking into account risk factors for breast cancer, the gap between women without diabetes and diabetics on drugs other than metformin vanished. But diabetics on metformin turned out to have a 25 percent lower cancer risk than their diabetes-free peers.

"This is an area of great excitement," said Pamela Goodwin, a breast cancer expert at Mount Sinai Hospital in Toronto, Canada, who wrote an editorial that appeared with the study.

"The evidence is coming together that metformin may actually have a clinically-relevant effect, but none of this is good enough to chance clinical practice just yet."

But she added that while the study is the best of its kind so far, it relies on observations instead of an actual experiment in which women are randomly selected to take metformin or not.

Goodwin and her colleagues are currently running a trial to test whether metformin can help ward off new tumors in women getting breast cancer treatment. Results are expected in three to four years. SOURCE: http://bit.ly/L86p7l

(Reporting from New York by Frederik Joelving at Reuters Health; editing by Elaine Lies and Bob Tourtellotte)



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Thursday, June 14, 2012

FDA reviews safety of innovative heart valve

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Freezer damages brain samples used to study autism

A freezer malfunctioned at a Harvard-affiliated hospital that oversees the world's largest collection of autistic brain samples, damaging a third of the scientifically precious specimens and casting doubt on whether they can be used in research.

The director of the Harvard Brain Tissue Resource Center said the loss was "devastating," particularly in light of the increasing demand for brain samples among scientists searching for the cause of autism and potential treatments.

"Over the last 10 years, the autism tissue program has been working very hard to get the autism community to understand the importance of brain donation," Dr. Francine Benes said. Now many of those samples have been compromised.

The freezer failed sometime late last month at the center, which is housed at McLean Hospital in the Boston suburb of Belmont. At least 54 samples earmarked for autism research were harmed. Many of them turned dark with decay.

However, an initial review indicates that the DNA in the samples is intact and can still be used for genetic research. It's unclear, however, whether the samples could be used for the full range of neuroscience needs.

Thirty-two of the brains had been cut in half, with one side placed in a formaldehyde solution and the other placed in the freezer. The samples in the solution remain available for all research projects, the hospital said.

The frozen tissue samples are normally maintained at about minus 80 degrees Celsius, but the temperature had reached about 7 degrees

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Noisy hospitals need Rx for quiet as patients rest

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Stem cells can be harvested long after death: study

"Stem cells are fed at the University of Connecticut's Stem Cell Institute in 2010. Some stem cells can lay dormant for more than two weeks in a dead person and then be revived to divide into new, functioning cells, scientists in France say. (AFP Photo/Spencer Platt)" title

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Brazil claims successful test of parasite vaccine

"Photo illustration. Brazilian researchers say they have successfully tested a vaccine against schistosomiasis, a disease caused by parasitic worms that afflicts more than 200 million people worldwide. (AFP Photo/Saul Loeb)" title

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HIV may have returned in 'cured' patient: scientists

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Anti Aging Eye Merchandise

June 13, 2012 by admin

As a result of the eyes are lacking fat and oil glands, their creams are necessary to assist soften and nourish the skin round the eyes. Some eye creams improve the firmness and texture of the skin, as well as hydrate the skin. There are some creams that swish fine lines, scale back puffiness, and take away dark circles round the eyes. Quality anti aging creams contains vitamins A and D as these vitamins are diminished within the skin when there is increased exposure to the sun. Many of these eye creams also contain Vitamin E and Aloe Vera. These nutrients create the skin around the eyes healthier and younger looking.There are others that increase collagen that stimulates growth of recent skin cells as well as serving to to repair damaged skin. Quality vision creams for dark circles can normally contain such ingredients as Kojic acid, Vitamin K, and hydroquinone.

These ingredients help to prevent bruising and they conjointly lighten the skin. Eye creams that remove wrinkles and puffiness will normally have such ingredients as alpha-hydroxy acids (AHA), peptides, caffeine, retinol, and vitamin C. The ingredients stimulate collagen production and firm the skin. When targeting both wrinkles and dark circles below the eyes, it’s suggested that one uses a cream that targets a mixture of skin problems. There is a new ingredient known as Hylexin that has shown promising results in reducing dark circles underneath the eyes.Peptides are an necessary ingredient as they’re very effective at reducing wrinkles. Merchandise with a high concentration of peptides will be quite expensive. Another ingredient, Hyaluronic acid, that can be found in eye creams, is essential to firming and hydrating the skin. In addition, they containing the ingredient ‘escinine,’ a botanical with anti-inflammatory properties, and manganese, a mineral that increases circulation, can drastically decrease underneath eye puffiness.There are all natural eye creams which will embrace Vitamins and minerals, natural oils like nutmeg oil, sunflower oil, and sweet almond oil, and ocean weed extracts, water/aqua, Avocado oil, rose distillate, glycerin, alcohol, pineapple extract, Beeswax, peanut oil, rose petal extract, Jojoba oil, Mango butter, fragrance essential oil, Shea butter, and a lot of more.As we tend to age, our skin becomes a lot of vulnerable to damage. This is often especially true for the skin around the eyes that makes using anti aging eye creams a vital part of a daily skin care routine. One must first determine what eye problem they need such as wrinkles, puffiness, or dark circles beneath the eyes, and then decide the eye cream that best meets their skin needs. You will soon see improved, healthier, and younger trying skin.

Anti Aging

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Skin Care: 8 Simple Ways To Get Rid Of Acne Without Prescription Drugs And Products

June 13, 2012 by admin

So what causes acne? Acne occurs when there is a build up of dead skin cells or something (ie. Oil, dirt and dust) in the follicles (tiny little canals that are connected to your pores and glands) on your skin which interacts with bacteria producing a pimple, whitehead or blackhead. If not treated correctly, acne can leave to permanent skin scarring which can lead to lower self-confidence and self-esteem.

As part of a healthy lifestyle and diet, it is hence important that we have and ensure we maintain healthy skin. I have thus listed out 8 simple and very effective ways of improving your skin appearance and reducing your risk of acne breakouts and pimples.

1. Wash your face twice a day

Washing your face twice a day helps to get rid of all the bacteria, grime, oil and dirt that you have gathered throughout the day. Wash it gently once in the morning and again at night to ensure that your skin is free of dust, dirt, dead skin cells and bacteria which will reduce the possibility of clogging. However, the reason why I only suggested washing it twice a day is that it is actually not a good thing to wash your face too much. Washing your face excessively can actually strip your face of its natural oils which could result in drier/ weaker skin as your skin gets dehydrated.

When washing your face, use lukewarm water as hot water can strip your skin off its important nutrients. Make sure you pat dry your face and use a mild soap of cleanser to help prevent breakouts. I recommend finding a gentler cleaner that would not strip the skin of its natural moisturizers.

2. Reduce your stress levels

Studies have shown that there is a high correlation between levels of stress and the level of acne breakouts and blemishes. This is because when we undergo stress, our body undergoes a chemical reaction to produce stress hormones which consequently produces more oils. This oil, called seburn, is produced by facial glands inside hair follicles which will travel up the follicle canal and take along dead skin cells with it. Once the oil reaches the surface, it forms a protective coating, effective sealing in the dead skin cells, blocking the pores and creating breakouts.

Thus, it is important to try and reduce stress in order to prevent acne problems. However, with deadlines, social obligations, work commitments, projects, etc, reducing stress is understandably not an easy thing to do. This is why it is important to learn to live a balanced lifestyle and have a balanced diet to try and maximize your potential for a more stress-free life. A good idea is to read up on how to increase your energy levels naturally so you can get more out of your day, and how to eat right.

3. Reduce the amount of times you touch your face.

I know this sounds incredibly stupid and ridiculously easy. But many of us dont realize that we touch our faces a lot. We play with our ears, rub our eyes, lean our chin/cheeks against our hands, etc and it is thus probably one of the hardest thing to not do!

The problem with touching your face is that the surface of your hands contains plenty of bacteria from the day to day things you have come into contact with. You pick up bacteria every time you open the door, shake hands, touch your computer, handle money, pay for food, etc. Consequently, your hands are the highest source of dirt, oil, bacteria and even viruses. Once these things come into contact with your face, they start clogging up your pores and/or irritate your skin which can result in pimple development.

Hence, ensure that you wash your hands throughout the day especially before youre about to consciously touch your face (ie. to apply makeup). You will reduce the build up of bacteria, grime and grease and hence, the possibility of pimple breakouts.

4. Review your make up

The thing about makeup is: it doesnt cause breakouts but it really doesnt help in preventing them either. To reduce the possibility of breakouts, try going for oil-free and organic makeups that are free from additives that could irritate sensitive skin. However, if you feel that your current makeup brand/selection isnt causing you too much grief, it should be perfectly fine to stick with it. Unfortunately, for those who are experiencing some problems, switching and trying out new brands may be the only way of discovering which brand of makeup is best suited for you and your skin. Remember, this will take patience, but if you keep track on what works and what doesnt, it will be worth it in the end.

Lastly on this point, always remember to wash your makeup off every time before you go to bed. This will give your pores and skin a chance to breathe and remain healthy.

5. Increase your vitamin A, B, C, E and zinc intake

Studies have shown that a deficiency in these vitamins could result in higher chance of acne development and breakouts.

In particular, zinc and vitamin c are well known to be extremely effective in boosting your immune system which consequently helps cure acne and blemishes as it ensures that your body is operating at its optimum level. Furthermore, deficiencies in these particular nutrients have shown to actually cause acne. Thus, it is important to have a balanced diet to ensure youre are consume adequate amounts of vitamin A,B,C,E and zinc intake.

6. Reduce your intake of processed and fatty foods.

I know we have all heard about it before, but fatty and processed foods are really andtrulybad for you. Unfortunately, consuming too much of these type of foods can really affect the healthiness of your skin. Consuming oily/fatty foods (though extremely tasty) affects your immune system, promoting the production of oil on your skin surface which will hence increase your risk of acne breakouts and pimples.

Thus, it is important to try and reduce your intake of these type of foods and make sure that you try to wash your face twice a day with a facial wash to help remove access oils that may have built up over the day.

7. Eat foods that are rich in Omega-3

Omega-3 fatty acids are excellent in helping to prevent breakouts as they ensure that cell membranes remain healthy so that nutrients can be transported efficiently to the cells. Furthermore as acne is a skin inflammation reaction to excess sebum (oil/grease on your face), Omega-3s anti-inflammatory and antibacterial effects will assist in the reduction of skin inflammation which will result in a reduction of acne.

Foods that are rich in Omega-3 include fish, fish oil, olive oils, walnuts and tofu. Or alternately, if due to circumstances you cant seem to incorporate enough Omega-3 rich foods in your diet, you can use supplements that are high in Omega-3 fatty acids.

8. Exercise

I know youre probably wondering how on earth could exercise help with your skins health and appearance. The great thing about exercise is that it reduces your bodys stress levels. Stress increases your skins natural oils which in greater amounts, leads to the clogging of pores and mass breakouts. Thus, by exercising, youre reducing stress on your body which indirectly affects your facial appearance. Furthermore, sweating from exercise helps to clear out your pores so that your dead skin cells will be flushed to the top, allowing less clogging to occur.

One very important thing to remember though, please shower after you have exercised. As sweat clears the pores of dead skin cells and leaves it at the top, the accumulation of these skin cells (if left for long enough) can lead to blockages which will eventually block (again) your recently cleared pores. In addition to this, when sweat evaporates, it leaves behind salt on your skin which encourages pore blockages. A good post-exercise facial product would be a moisturizing cleanser to help clean all or the impurities from your face and to help replenish the moisture on your face that may have been lost during your work out.

So there you have it, 8 simple ways to healthier looking skin. Combating acne is really a case of looking after your skin and your body. Ensure that you are having a proper diet, drinking lots of water and living a balanced lifestyle and your skin, body and acne problems will look after themselves. The results may not be overnight, but in the long term it is the most effective way of improving your acne condition permanently.

Good Luck!



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Affordable Cosmetic Dental Work By Dayo Dental

June 13, 2012 by admin

Cosmetic dental work may sound complicated and expensive, but in reality it can be as cheap as you want it to be. People generally go in for cosmetic dental treatments to enhance the appearance of their teeth. Whether it is to make your crooked teeth look straighter or to improve the general appearance of your teeth and to make them shine, people go in for cosmetic dental work. It is commonly understood that these treatments are best if you have a healthy set of teeth and gums.

A general understanding of teeth would tell you that the teeth and gums are to be treated for cavity and decay before cosmetic dental work.

Colored fillings seem to be the most common form of cosmetic dental work. Not only are fillings used to fill holes caused by decay or cavity, but they are also being used as attractors. Amalgam fillings are being replaced by colored fillings because they are more natural-looking when compared to the silver color of the former. However, when it comes to durability, amalgam fillings are better than the colored fillings because they are able to assist in grinding and chewing effectively.

Tooth whitening is another module of cosmetic dental work this is generally used to lighten the natural shade of the teeth. Whitening agents are abrasive and tend to remove the top layer of the teeth bringing in a natural shine rather than giving an artificial white coating on the teeth.

Veneers are generally used to give the appearance of straighter teeth even if they are chipped or damaged. They are made of ceramic materials that can be placed on the tooth. Not only do they gel well with the teeth, but also they are available in different thickness to fill the gaps between teeth. This is one of the few methods which do not require the use of anesthesia. Veneers have to be custom-made depending on the requirement of the teeth line and have to be cemented on the surface. Crowns, inlays and on-lays are also for the same purpose and filling in chips and broken teeth.

Dental

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Anti aging genes discovered

June 13, 2012 by admin

The Fountain of Youth, an anti aging nectar that prolongs time spend on earth; a nectar that can cure every health problem; a nectar, unfortunately, that can be found only in fictional stories. In spite of its fictional existence, the fountain of youth is a kick-start motif for scientist search for longer life span. Youth is the greatest period in everyman’s life and forever young a common wish.

Scientist claim that the root of longer life span lies in human’s genes. It is not something that you can gain reaching certain age and it is not something that you can make by consuming special drugs. Centurion is created from birth. Through out the years scientists have made many researches concerning longer life-span situation. One type of research is published in Science and has two parts.

The first part is called GWAS, or “genome-wide association study.” About 1,000 people over 100 years old were part of the New England Centenarian Study.

The obtained data was compared to a normal aging group of people; their number was also about 1,000. 70 genes were found in centenarians, repeating the study to a smaller group gave the result of 33 genes.

To make sure that everything is fair-and-square, disease-causing genes were examined in both of the groups, centenarians and normal aging people. It was confirmed that centenarians were exposed to disease as much as the normal aging people. The interesting thing is that strong immunity was given to the centenarians by the genes, ergo, longer healthy days.

150 people, centenarians and normal aging people, underwent the model research without the knowledge of who has 70 genes of longer life. The model was 77 % accurate in his prediction to which group the subject belong to. It gave 19 different genetic combinations in the centenarians.

An interesting fact about this is that 15 % had those combinations, meaning that 15 % of us should reach the age of 100 years old, and even more. But reality bites with the result of 1 in 6,000.

There are scientists that greet these results and consider them good data for future research. There are others that counter them stating that the number of people in the research is not enough.

Science confirms the fact that genes have major role in longer life. But it also, firmly states, that if you don’t take care of your body, it won’t be able to take care of you. Healthy nutrition and exercising on a regular schedule is a perfect natural way to contribute years on your calendar. Every body is undergoes aging; so, make it a healthy aging process.

 

Anti Aging

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Feed Your Skin, Starve Your Wrinkles: Eat Your Way to Firmer, More Beautiful Skin with the 100 Best Anti-Aging Foods

At long last, a book that tells all about the connection between diet and health and the look of your skin. Everyone interested in beautiful skin should read this book!

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