Calcium and Vitamin D Reduces the Risk for Breast and Colon Cancer

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Magnesium Reduces the Risk for Colon Cancer

Magnesium deficiency is prevalent in just about any person whose health is struggling or slipping into a trend in the wrong direction. This can be predicted because magnesium is required to run many genes and enzymes, reduce inflammation, and enhance genomic stability.  Thus, it is frequently lacking in the context of struggling health. A new study shows that for each increase of 100 mg of magnesium per day, the risk of colon cancer drops by 13 percent.

In individuals who are not overweight magnesium is shown to be protective. In individuals who are overweight magnesium is shown to be highly protective. This is because overweight individuals are living in an inflammatory state more likely to have DNA damage from this inflammation and accompanying free radical damage. In other words, the worse off a person’s health is, the more he or she needs higher levels of magnesium for protection.

I recommend up to 800 mg per day of supplemental magnesium for individuals who are under high stress or overweight. This is a basic precaution for protection. As stress levels come down and weight improves, then 400 mg is likely adequate.

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Olive Oil Intake Reduces Mortality

A study tracking 40,622 Spanish citizens over a 13 year period found that those who had the highest consumption of olive oil, compared to little or no consumption, had a 26 percent risk reduction in death from any cause.

The study also identified a 44 percent risk reduction in death from cardiovascular disease.  While olive oil is a monounsaturated fatty acid, it is known to work synergistically with essential fatty acids, such as DHA Docosahexaenoic acid Essential omega 3 fatty acid integral to the health of all cell membranes, nerve and brain function. Must be gotten through the diet via cold water oceanic fish or some very limited plant sources or taken as a supplement., to enhance their incorporation into cell membranes.

The bottom line is that olive oil should be part of the fat intake of a healthy diet, especially for those who are concerned about their cardiovascular health.

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Apple peel compound boosts brown fat, reduces obesity in mice

ScienceDaily (June 20, 2012) — Obesity and its associated problems such as diabetes and fatty liver disease are increasingly common global health concerns. A new study by University of Iowa researchers shows that a natural substance found in apple peel can partially protect mice from obesity and some of its harmful effects.

See Also:Health & MedicineObesityFitnessDiet and Weight LossPlants & AnimalsMiceRodentsCell BiologyLiving WellReferenceSaturated fatAdipose tissueDiabetes mellitus type 2General fitness training

The findings suggest that the substance known as ursolic acid reduces obesity and its associated health problems by increasing the amount of muscle and brown fat, two tissues recognized for their calorie-burning properties.

The study, which was published June 20 in the journal PLoS ONE, was led by Christopher Adams, M.D., Ph.D., UI associate professor of internal medicine and a Faculty Scholar at the Fraternal Order of Eagles Diabetes Research Center at the UI.

"From previous work, we knew that ursolic acid increases muscle mass and strength in healthy mice, which is important because it might suggest a potential therapy for muscle wasting," Adams says. "In this study, we tested ursolic acid in mice on a high-fat diet -- a mouse model of obesity and metabolic syndrome. Once again, ursolic acid increased skeletal muscle. Interestingly, it also reduced obesity, pre-diabetes and fatty liver disease.

"Since muscle is very good at burning calories, the increased muscle in ursolic acid-treated mice may be sufficient to explain how ursolic acid reduces obesity. However, we were surprised to find that ursolic acid also increased brown fat, a fantastic calorie burner. This increase in brown fat may also help protect against obesity."

Until quite recently, researchers believed that only infants had brown fat, which then disappeared during childhood. However, improved imaging techniques have shown that adults do retain a very small amount of the substance mostly in the neck and between the shoulder blades. Some studies have linked increased levels of brown fat with lower levels of obesity and healthier levels of blood sugar and blood lipid, leading to the suggestion that brown fat may be helpful in preventing obesity and diabetes.

The UI team, which also included Steven Kunkel, Christopher Elmore, Kale Bongers, Scott Ebert, Daniel Fox, Michael Dyle, and Steven Bullard, studied mice on a high-fat diet over a period of several weeks. Half of the animals also received ursolic acid in their high-fat food. Interestingly, mice whose diet included ursolic acid actually ate more food than mice not getting the supplement, and there was no difference in activity between the two groups. Despite this, the ursolic acid-treated mice gained less weight and their blood sugar level remained near normal. Ursolic acid-treated mice also failed to develop obesity-related fatty liver disease, a common and currently untreatable condition that affects about one in five American adults.

Further study showed that ursolic acid consumption increased skeletal muscle, increasing the animals' strength and endurance, and also boosted the amount of brown fat. Because both muscle and brown fat burn calories, the researchers investigated energy expenditure in the mice and showed that ursolic acid-fed mice burned more calories than mice that didn't get the supplement.

"Our study suggests that ursolic acid increases skeletal muscle and brown fat leading to increased calorie burning, which in turn protects against diet-induced obesity, pre-diabetes and fatty liver disease," Adams says. "Brown fat is beneficial and people are trying to figure out ways to increase it. At this point, we don't know how ursolic acid increases brown fat, or if it increases brown fat in healthy mice. And, most importantly, we don't know if ursolic acid will benefit people. Our next step is to determine if ursolic acid can help patients."

The research was supported by funding from the Fraternal Order of Eagles Diabetes Research Center at the University of Iowa, the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health (grant 5R01AR059115-03), the Department of Veterans Affairs, and the University of Iowa Research Foundation.

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Marijuana Reduces MS Symptoms

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