Showing posts with label Mechanisms. Show all posts
Showing posts with label Mechanisms. Show all posts

Wednesday, March 28, 2012

Silymarin Helps Bones by Multiple Mechanisms

Silymarin (milk thistle) is best known for its role in protecting your liver and defending you from multiple toxins commonly found in today’s environment, not to mention alcohol. A new study shows that this potent antioxidant herb modulates multiple genes in favor of helping you build bone and prevent bone loss.

Maintaining healthy bones requires additional steps beyond adequate calcium, vitamin D, protein, and other cofactor nutrients that are required for bones to form.  There is a dynamic bone rejuvenating process going on which must be kept functioning properly especially as you age.  Bone-building carpenter cells called osteoblasts must keep up with the demo crew run by osteoclasts Type of bone cell that removes old, damaged bone by the process bone resorption..  You need both types of cells working in balance with each other.  A key problem occurs when osteoclasts Type of bone cell that removes old, damaged bone by the process bone resorption. run wild, leading to inappropriate bone loss.  Science now demonstrates that this problem is caused by the impact of excessive inflammation within bone, reflected in part by your overall trend of wear and tear.

Nutrients that help turn off inflammatory genes within bone help to calm down the problem of osteoclasts Type of bone cell that removes old, damaged bone by the process bone resorption. going wild.  Nutrients such as DHA Docosahexaenoic acid Essential omega 3 fatty acid integral to the health of all cell membranes, nerve and brain function. Must be gotten through the diet via cold water oceanic fish or some very limited plant sources or taken as a supplement., tocotrienol Specialized form of vitamin E. Powerful antioxidant showing positive benefits for cholesterol, cardiovascular, neurological health and cancer risk reduction. E, quercetin, magnesium, and many others have been shown to assist in this situation.  We can now add silymarin to this list, as the new study demonstrates that it has a potent effect on stopping excessive osteoclast activity by regulating key inflammatory genes within bone cells. 

Additionally, silymarin was shown to promote the growth of new bone tissue by stimulating many of the key systems involved with how osteoblasts carry out their bone-building activities.  This included enhanced calcium deposition into new bone, up regulation of key bone-building enzyme called alkaline phosphatase, and stimulation of collagen and connective tissue growth factors needed for new bone to form.

It is somewhat surprising that silymarin would be able to influence so many aspects of bone health.

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Supplements that contain silymarin
Related Entries:

Quercetin Supports Bone Health
Bone Quality is of the Utmost Importance to Bone Health
Research Says Take Supplements of Calcium, Vitamins D & K for Bones – Not Bisphosphonate Drugs
Gamma Tocotrienol Assists Bone Strength
Is Long Life in Your Bones?

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