Friday, August 3, 2012

Dairy Fat Intake Linked to Better Cardiovascular Health and Less Risk for Diabetes

The idea that all saturated fat is a health evil permeates the defunct dogma of Western medicine and its Big Pharma toxic pill pushers. It has probably never occurred to them that saturated fat is perhaps the best calorie for energy production, and quite good for long lasting energy if you don’t consume too much. Two studies in the American Journal of Clinical Nutrition continue a long list of studies questioning the assertion that saturated fat causes disease, in and of itself.

The first study comes from researchers at the University of Texas School of Public Health. Researchers followed a multiethnic group of 5,209 adults, aged 45 – 84, for 10 years while tracking their diets, and looking into the diets of those who developed cardiovascular disease (316 cases) during the course of the study.  They found that those with the highest intake of saturated fat from dairy had up to a 38 percent risk reduction for developing cardiovascular disease. This is a rather shocking finding for the promoters of skim milk and other no-fat dairy.  On the other hand, the study found that those with the highest intake of saturated fat from meat had up to a 48 percent increased risk for cardiovascular disease. Furthermore, replacing two percent of meat calories with dairy fat lowered overall risk by 25 percent.

It is likely that many of the cofactor nutrients in dairy help to metabolize the saturated fat, helping to make it a cardio friendly food. In defense of meat fat, my opinion is that it is really an issue of how the beef was raised, and what it was fed. Many sickly and pathetically unhealthy animals have lived on toxic junk food their entire lives and had no exercise – of course their fat is not worth eating. There is no substitute for quality raised and fed meat, such as range raised and grass fed.

Furthermore, those who eat the most toxic meat are also likely to be eating other junk food and also lacking fiber, fruit, and vegetables. This is not rocket science.

In the second study Danish researchers evaluated 340,234 adults from eight European countries for their intake of dairy and risk of type 2 diabetes. This is a very large study representing four million human years of follow up. Researchers found that dairy intake, regardless of the amount of fat taken in, was not linked to the development of type 2 diabetes. To the contrary, certain types of dairy such as cheese and yogurt were linked to a 12 percent risk reduction. 

Americans should keep in mind that the quality of dairy products is much higher in Europe. It is highly advised that Americans consume organic dairy and cheeses of higher quality.

The simple fact of the matter is that there is no need to fear saturated fat. If you consume high quality forms of saturated fat as a reasonable portion of your daily calories, along with omega-3 oils like DHA Docosahexaenoic acid Essential omega 3 fatty acid integral to the health of all cell membranes, nerve and brain function. Must be gotten through the diet via cold water oceanic fish or some very limited plant sources or taken as a supplement., fruit, vegetables, and adequate dietary fiber, then saturated fat is likely to be an energy sustaining friend, which actually helps your metabolism run better, and is not at all associated with risk for disease.

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Most with celiac disease unaware of it; others go gluten-free without diagnosis

ScienceDaily (July 31, 2012) — Roughly 1.8 million Americans have celiac disease, but around 1.4 million of them are unaware that they have it, a Mayo Clinic-led analysis of the condition's prevalence has found. Meanwhile, 1.6 million people in the United States are on a gluten-free diet even though they haven't been diagnosed with celiac disease, according to the study published July 31 in the American Journal of Gastroenterology.

See Also:Health & MedicineChronic IllnessAlzheimer's ResearchDiseases and ConditionsHealthy AgingCholesterolJoint PainReferenceGluten-free, casein-free dietGlutenOatRestless legs syndrome

Researchers have estimated the rate of diagnosed and undiagnosed celiac disease at similar levels prior to this study, but this is the most definitive study on the issue. "This provides proof that this disease is common in the United States," says co-author Joseph Murray, M.D., a Mayo Clinic gastroenterologist. "If you detect one person for every five or six (who have it), we aren't doing a very good job detecting celiac disease."

Celiac disease is a digestive disorder brought on when genetically susceptible people eat wheat, rye and barley. A gluten-free diet, which excludes the protein gluten, is used to treat celiac disease. Roughly 80 percent of the people on a gluten-free diet do so without a diagnosis of celiac disease.

"There are a lot of people on a gluten-free diet, and it's not clear what the medical need for that is," Dr. Murray says. "It is important if someone thinks they might have celiac disease that they be tested first before they go on the diet."

To determine its prevalence, researchers combined blood tests confirming celiac disease with interviews from a Centers for Disease Control and Prevention (CDC) nationwide population sample survey called National Health and Nutrition Examination Survey. The survey, designed to assess the health and nutrition of U.S. adults and children, is unique in that it combines interviews and physical examinations.

Researchers found that celiac disease is much more common in Caucasians.

"In fact, virtually all the individuals we found were non-Hispanic Caucasians," says co-author Alberto Rubio-Tapia, M.D., a Mayo Clinic gastroenterologist. But previous research in Mexico has shown that celiac disease could be just as common as it is in the U.S.

"So that is something we don't fully understand," Dr. Rubio-Tapia says. The study found the rate of celiac disease in the U.S. is similar to that found in several European countries.

The research was funded in part by the National Institutes of Health and the CDC. Study authors include James Everhart, M.D., from the National Institute of Diabetes and Digestive and Kidney Disease; Jonas Ludvigsson, M.D., Ph.D., from Orebro University Hospital and the Karolinska Institutet; and Tricia Brantner from Mayo Clinic.

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Thursday, August 2, 2012

Stress during pregnancy leads to abdominal obesity in mice offspring

ScienceDaily (July 31, 2012) — New research suggests that the neuropeptide Y in plasma and its Y2 receptor in visceral fat play an important role in obesity.

See Also:Health & MedicineObesityDiet and Weight LossStaying HealthyMind & BrainDieting and Weight ControlNutrition ResearchStressReferenceAppetiteNutrition and pregnancyGeneral fitness trainingDiabetes mellitus type 2

A new report involving mice suggests that a relationship exists between maternal metabolic or psychological stress and the development of obesity, type 2 diabetes, and metabolic syndrome in her offspring. What's more, the report shows that if the stress cannot be reduced or eliminated, manipulating the neuropeptide Y (NPY) system in visceral fat may prevent maternal stress-induced obesity from occurring in the next generation. This discovery is reported in the August 2012 issue of The FASEB Journal.

"Obesity is a worldwide disease. Here we found that maternal stress, psychologically and metabolically, increases abdominal obesity and glucose intolerance in the next generation in a sex-specific manner, which is mediated by the NPY system in visceral fat," said Ruijun Han, a researcher involved in the work from the Department of Integrative Biology and Physiology, Stress Physiology Center at the University of Minnesota. "Our study suggested that NPY in the platelet-rich plasma and its Y2 receptor in the visceral fat, play an important role in maternal stress-programmed abdominal obesity and metabolic syndrome in offspring."

To make this discovery, Young and colleagues fed different groups of pregnant mice a low protein diet during pregnancy and lactation; a normal protein diet during pregnancy and lactation; or a low protein diet only during pregnancy. After weaning, all the pups were fed high fat diets for 18 weeks, and metabolic parameters and expression of NPY system in periphery tissues were monitored and measured.

"There are a lot of reasons why expectant mothers should not be under stress," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "and this report adds yet another reason. What's most interesting, however, is that it provides some insight into how we can counter the negative effects of stress, even when it's not possible to reduce or eliminate the stressors themselves."

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Vitamins And Supplements to Take on the Clean Diet

making you an efficient fat burning machine!

2. Vitamin D

Vitamin D assists with the absorption of nutrients including calcium and phosphorus. This vitamin also does wonders for your skin, promoting softer, smoother skin and reduces the appearance of fine lines. If you’re stressed out or tense from work this helps alleviate that along with body aches and pains.

3. Magnesium

If you work out, Magnesium is great for muscle repair. This vitamin also plays a part in our cardiovascular health as well as making bones stronger and assists with absorption of other minerals like calcium and potassium. For us ladies it helps with pre-menstrual cramps and relieves symptoms of menopause.

4. Chromium

If you are a sweet tooth like me you might need a little help with the cravings. Chromium aids with the regulation of insulin levels. New research has shown that chromium can help reduce food intake, suppress hunger levels and minimise food cravings. The great thing about this vitamin is that not only does it suppress your appetite, but it reduces your cravings for high-fat foods!

5. B12

Are you feeling tired and lazy? You could be vitamin B12 deficient. This vitamin is needed to convert carbs into glucose which then turns into energy so this will help you feel more energised and helps with depression and stress. This is a good one for keeping skin, nails and hair healthy too!

6. Zinc

I mainly take Zinc for healthy skin. Zinc helps with new cell growth so it’s essential for healthy and brighter looking skin. Because our insides are all made of cells zinc helps keep our intestines and gut healthy and well maintained. Zinc also helps building your immune cells that protect you from disease so make sure you supplement with zinc especially when you get a cold!

There are many other supplements to assist with eating clean to look into for your personal needs, so do some research on your specific concerns. This is a good place to start and gives you some assistance when you’re not getting what you need from our food sources. These supplements will help you feel better and look better. In conjunction with a clean diet and lifestyle you are on your way to long and healthy life!

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All-they-can-eat diet for lab mice and rats may foster inaccurate test results

ScienceDaily (July 18, 2012) — The widespread practice of allowing laboratory rats and mice to eat as much as they want may be affecting the outcome of experiments in which scientists use these "test-tubes-on-four-feet" to test new drugs and other substances for toxicity and other effects. That's the conclusion of a new analysis published in ACS' journal Chemical Research in Toxicology.

Share This:See Also:Health & MedicineNutritionAlzheimer's ResearchCancerPlants & AnimalsMiceAnimalsFoodReferenceForensic toxicologyMouseHouse mouseNanomedicine

Laboratory mice and rats serve as stand-ins for people for research that cannot be done on humans. In the article, Gale Carey and Lisa Merrill point out that the millions of lab rodents used in laboratory studies each year have a nutritional status that is different from other test animals. While other test animals are fed meals, rodents have round-the-clock access to food. And eat they do, gaining more weight and more body fat than meal-fed rodents. The authors cite other research indicating that lab rodents with free access to food tend to develop abnormally high blood fat levels, high cholesterol, nerve and heart damage, cancer and other disorders.

Their analysis of 54 studies concluded that having free access to food is likely to affect the results of tests for the toxicity and cancer-causing effects of new drugs and other substances in rodents, and could be the reason why such studies have been varying so much in recent years. "Therefore, it is crucial that feeding regimen be carefully considered in designing toxicology experiments," say the authors.

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How malnutrition leads to inflamed intestines

ScienceDaily (July 24, 2012) — More than one billion people in poor countries are starving, and malnutrition remains a major problem even in rich countries, making it a leading cause of death in the world. For over a hundred years, doctors have known that a lack of protein in the diet or low levels of amino acids, the building blocks of proteins, can lead to symptoms like diarrhoea, inflamed intestines and other immune system disorders, which weaken the body and can be fatal. However, the molecular mechanism which explains how malnutrition causes such severe symptoms has been largely unexplored.

Now a research group led by Josef Penninger, the director of the Institute of Molecular Biotechnology (IMBA) in Vienna, Austria, in cooperation with Philip Rosenstiel, University of Kiel, Germany, has found a molecular explanation for the increased susceptibility to intestinal inflammation in malnutrition.  The researchers were studying an enzyme which helps to control blood pressure, kidney failure in diabetes, heart failure and lung injury, called the Angiotensin Converting Enzyme 2, or ACE2.  This enzyme was identified as the key receptor for SARS virus infections, but the researchers also discovered an entirely new function.  ACE2 controls the way our intestines take in amino acids from our food, via amino acid transporters, and in particular the uptake of the essential amino acid tryptophan.

Too little tryptophan alters our natural immune system, which changes the types of bacteria which can live in our bowels and guts, leading to higher sensitivity and eventually diarrhoea and inflamed intestines.  Increasing the intake of tryptophan in their diet provided relief for mice suffering from intestinal inflammation. The mixture of bacteria returned to normal, the inflammation died down, and the mice also became less susceptible to new attacks.

"The research shows how the food we eat can directly change the good bacteria in our intestines to bad bacteria and so influence our health”, says Thomas Perlot, the first author of the study. “Our results might also explain nutritional effects that have been known for centuries and provide a molecular link between malnutrition and the bacteria living in our intestines. This discovery could be used in the future to treat patients with a simple regulated diet or by taking tryptophan as a food supplement.  And there is hardly any risk of side effects from artificially increasing an amino acid found in the normal diet.”

Josef Penninger, the lead author, says “I have studied ACE2 for more than 10 years and was completely stunned by this novel link between ACE2 and amino acid balance in the gut. Biology continues to surprise me. Up to a billion people in the world are malnourished, especially the poor and disadvantaged. In Austria alone, around 80,000 people suffer from a chronic inflammatory bowel disease like ulcerative colitis or Crohn's disease. I hope that our findings have opened a door to a better molecular understanding how malnutrition affects human health. Whether simple tryptophan diets can indeed cure the effects of malnutrition in humans now needs to be carefully tested in clinical trials.”

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Asthma Common Among Olympic Athletes

HealthDay – 3 mins 8 secs ago THURSDAY, Aug. 2 (HealthDay News) -- Asthma and airway hyper-responsiveness are the most common chronic conditions among Olympic athletes, affecting about 8 percent of the competitors, according to a new study.

The Australian researcher suggested the conditions may be linked to the athletes' intense training, particularly those who participate in endurance sports or winter sports. The inhalation of cold air contributes to airway damage.

Airway hyper-responsiveness involves marked narrowing of the airways in response to some kind of outside trigger.

"Inhaling polluted or cold air is considered an important factor which might explain the cause in some sports, but not in all," explained study author Kenneth Fitch, of the University of Western Australia, in a university news release. "The quality of inhaled air could be harmful to the airways, but does not cause the same effect in all sports."

Fitch counted the number of athletes with asthma and airway hyper-responsiveness from the five Olympic games between 2002 and 2010. He identified the athletes by tracking the use of inhaled beta-2 agonists, an anti-asthma drug commonly used by top athletes.

In 2001, the International Olympic Committee recognized the increased use of the drug between 1996 and 2000, and issued a new rule requiring athletes to provide proof of their condition to safeguard the health of Olympic athletes, not as an anti-doping measure, according to the news release.

Fitch noted that athletes with asthma have routinely beaten their opponents. He added, however, there is no proof that treatments for the condition improved their performance. He suggested that training harder than other athletes could help explain why many athletes develop asthma or airway hyper-responsiveness as adults.

The study was published online in the British Journal of Sports Medicine.

More information

The U.S. National Heart, Lung, and Blood Institute provides more information on asthma.



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Opioid receptors as a drug target for stopping obesity

ScienceDaily (July 31, 2012) — New research demonstrates that blocking the delta opioid receptor in mice created resistance to weight gain and stimulated gene expression promoting non-shivering thermogenesis.

See Also:Health & MedicineDiet and Weight LossObesityFitnessMind & BrainDieting and Weight ControlOpiumNutrition ResearchLiving WellReferenceDetox dietSouth Beach dietCalorie restricted dietAdipose tissue

Imagine eating all of the sugar and fat that you want without gaining a pound. Thanks to new research published in The FASEB Journal, the day may come when this is not too far from reality. That's because researchers from the United States and Europe have found that blocking one of three opioid receptors in your body could turn your penchant for sweets and fried treats into a weight loss strategy that actually works. By blocking the delta opioid receptor, or DOR, mice reduced their body weight despite being fed a diet high in fat and sugar. The scientists believe that the deletion of the DOR gene in mice stimulated the expression of other genes in brown adipose tissue that promoted thermogenesis.

"Our study provided further evidence that opioid receptors can control the metabolic response to diets high in fat and sugar, and raise the possibility that these gene products (or their respective pathways) can be targeted specifically to treat excess weight and obesity," said Traci A. Czyzyk, Ph.D., a researcher involved in the work from the Department of Physiology at the Mayo Clinic in Scottsdale, Arizona.

Scientists studied mice lacking the delta opioid receptor (DOR KO) and wild type (WT) control mice who were fed an energy dense diet (HED), high in fat and sugar, for three months. They found that DOR KO mice had a lean phenotype specifically when they were fed the HED. While WT mice gained significant weight and fat mass on this diet, DOR KO mice remained lean even though they consumed more food. Researchers then sought to determine how DOR might regulate energy balance and found that DOR KO mice were able to maintain their energy expenditure levels, in part, due to an increase in non-shivering thermogenesis. This was evidenced by an increase in thermogenesis-promoting genes in brown adipose tissue, an increase in body surface temperature near major brown adipose tissue depots, and the ability of DOR KO mice to maintain higher core body temperatures in response to being in a cold environment.

"Don't reach for the ice cream and doughnuts just yet," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "We don't know how all this works in humans, and of course, a diet of junk food causes other health problems. This exciting research identifies genes that activate brown adipose tissue to increase our burning of calories from any source. It may lead to a safe diet pill in the future."

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Common Skin Cancer a Chronic Condition, Study Says

HealthDay – 3 mins 1 sec ago THURSDAY, Aug. 2 (HealthDay News) -- Here's yet another reason to go easy on the tanning this summer: A new study affirms that basal cell carcinoma, the most common form of skin cancer, should be viewed as a chronic disease.

That's because once most people have a single occurrence, they are at risk of getting another.

"Basal cell carcinoma has generally been viewed as something that comes up, is treated and cured," said Dr. Martin Weinstock, a study co-author and professor of dermatology at the Warren Alpert Medical School at Brown University in Providence, R.I. "For someone with an isolated lesion, that's a reasonable way of looking at it. But most people are constantly at risk of this and will be getting more."

The study confirmed what was commonly understood about the disease: a prior history of basal cell carcinoma is the greatest risk for another lesion. But the research found that eczema may also predict a recurrence among those at high risk for the disease. Those with a family history of eczema had a 1.54 times greater risk than those without.

Older age, sun sensitivity, intense sun exposure before age 30, and use of certain blood pressure-lowering medications (angiotensin-converting enzyme inhibitors or angiotensin receptor blockers) were also associated with increased risk.

Why would eczema, a chronic skin disorder that involves scaly and itchy rashes, be associated with basal cell carcinoma? Weinstock said it's unclear. "There may be some differences in these people's immune systems compared to people without eczema," he said, noting that other investigators need to confirm the findings.

Having other types of skin cancer or actinic keratoses (scaly or crusty growths caused by sun damage) did not appear to raise the chances for basal cell carcinoma.

The study was published online July 19 in the Journal of Investigative Dermatology and funded by the U.S. Department of Veterans Affairs. It involved more than 1,100 people, nearly all men, all veterans, with a median age of 72.

On average, each participant had more than three instances of basal cell cancer or squamous cell cancer (another type of skin cancer) before participating in the research. During the study period, 44 percent developed new basal cell cancers, and those with the most basal cell cancers in the five years before the study had the most recurrences.

Study participants with more than five prior basal cell cancers were nearly four times as likely to develop a new one as those with one or no prior skin cancers. And their risk was twice as high as those with three previous skin cancers, the study found.

Now the most common cancer in the United States, basal cell carcinoma begins in the outer layer of the skin, often as a small white or flesh-colored bump that grows slowly and sometimes bleeds. While these cancers rarely spread, they must be removed or treated, usually in a physician's office with local anesthetic.

Weinstock said researchers are eager to find a preventive medication to guard against the recurrence of basal cell carcinoma. Last year a team he led concluded that topical tretinoin did not prevent new basal cell cancers in high-risk patients. Now he is involved in a study looking at whether 5-Fluorouracil, a compound used to treat actinic keratoses, may prevent basal cell cancer when given intravenously.

Dr. Jean Tang, an assistant professor in the department of dermatology at Stanford University School of Medicine who is familiar with the study, said the most important thing for patients to know is that if you have had a basal cell carcinoma, you have a 44 percent chance of getting another.

"This study doesn't change any clinical guidelines or recommendations," she added. Current advice still stands: "Get an annual skin assessment by your dermatologist," she said.

More information

To learn more about skin cancer, visit the U.S. National Cancer Institute.



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Health Highlights: Aug. 2, 2012

HealthDay – 2 mins 30 secs ago Here are some of the latest health and medical news developments, compiled by the editors of HealthDay:

FDA Approves Ingestible Medical Sensor

The U.S. Food and Drug Administration announced that it has approved an ingestible medical sensor that reports vital information on a patient's health back to his or her doctor.

The device, from Proteus Digital Health Inc., is only about the size of a grain of sand and had already been approved by European health officials last year, CBS News reported. Once swallowed, it sends out information on whether patients are taking their medications as instructed, as well as data on vital signs.

The sensor is designed so that it can be placed inside a pill or other consumable and it is powered by stomach fluid, CBS said. It transmits information to a patch on the patient's stomach, and that data is then relayed to a cell phone app to the patient and, with his or her permission, to their caregiving team.

"About half of all people don't take medications like they're supposed to," Eric Topol, director of the Scripps Translational Science Institute in La Jolla,Calif., told the journal Nature.

"This device could be a solution to that problem, so that doctors can know when to rev up a patient's medication adherence," said Topol, who is not affiliated with the device's maker.

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Free Contraception, Well-Woman Visits Tied to Health Care Reform Begin

Starting Wednesday, up to 47 million American women can now gain free access to contraception, well-woman visits, STD screening and other benefits linked to the Affordable Care Act, CBS News reported.

"Women deserve to have control over their health care," Department of Health and Human Services (HHS) Secretary Kathleen Sebelius wrote on a blog posted on Healthcare.gov. "Too often, they have gone without preventive services, worrying about what even a $20 insurance co-pay would mean to their families' budgets and choosing to pay for groceries or rent instead. But now, thanks to the health care law, many women won't have to make that choice."

Starting Aug. 1, women will not have provide a co-pay for well-woman visits (including annual check-ups or more if doctors deem necessary); contraceptives and contraception counseling; HPV testing every three years for women aged 30 or over; annual sexually transmitted disease counseling, including HIV screening/counseling; domestic violence screening and counseling; screening for gestational diabetes and breast-feeding support, supplies and counseling.

The new benefits currently only apply to women who are enrolled in a health insurance plan, CBS News notes, although more uninsured women are expected to be included as health care reform is fully implemented.

The free services that kick in Wednesday join other no-fee, preventive health measures, such as mammography screening, cervical cancer screenings (via the Pap smear) and prenatal services, that are already covered by the Affordable Care Act.

Not everyone supports the changes, however. According to CBS News, Catholic groups have filed 12 lawsuits in 43 courts across the country to block the provision to supply contraception free of charge.

"The implementation of this policy marks the beginning of the end of religious freedom in our nation," Christen Varley, executive director of Conscience Cause, said in a statement.

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When Parents Get Active, So Do Kids: Study

HealthDay – 5 mins ago THURSDAY, Aug. 2 (HealthDay News) -- Parents who want to increase the amount of exercise their children get should become more active themselves, according to a new study.

"It has long been known that parent and child activity levels are correlated," study author Kristen Holm, an assistant professor of medicine at National Jewish Health in Denver, said in a news release. "

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Jewish communities to coordinate debate on circumcision

"An eight day-old baby is held during his circumcision ceremony in Haifa in 2006. Austria's Jewish community (IKG) said Monday it was working jointly with its German and Swiss counterparts to keep religious circumcision legal, after repeated calls for an end to the practice. (AFP Photo/Menahem Kahana)" title

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